Pattern, Management, and Outcome of Poisoning in a Tertiary Care Hospital

Authors

DOI:

https://doi.org/10.22502/jlmc.v6i1.201

Keywords:

antidote, insecticide, organophosphorus, poison, suicide

Abstract

Introduction: Poisoning is a significant global public health problem. The appropriate management of poisoning at emergency needs accurate assessment and immediate treatment. The immense chance for better outcomes occurs with early diagnosis and treatment. This study was conducted to assess pattern, management, and outcome of poisoning in tertiary care hospital.

Methods: An observational cross-sectional study was conducted in which records of patients with a diagnosis of poisoning over a period of four years were reviewed.

Results: A total of 138 patients were included in the study. A majority (63%) of them were females. Most (67.4%) were managed by general or supportive measure only. Gastric lavage was done in 60% of total patients while 52.9% patients received activated charcoal. Pralidoxime and atropine was received by 51.1% of patients treated with specific antidote. All the antidotes were administered through intravenous route. Regarding outcome, 89.9% were completely recovered. Suicidal poisoning was significantly higher in married as compared to unmarried patients (p = 0.029). Similarly, there was a significant relationship between occupation of the patients and manner of poisoning (p = 0.003). Outcome of treatment had a significant association with the manner of poisoning (p < 0.001). Further analysis revealed that the patients who expired in the hospital were more likely to ingest poison accidentally.

Conclusion: Suicidal poisoning is common and females are more susceptible. Insecticide and rodenticide are the commonly ingested poisons. Treatment outcome of poisoning cases is generally favorable.

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Author Biographies

  • Naresh Karki, Lumbini Medical College

    Lecturer,

    Department of Pharmacology

  • Vijay Singh, Lumbini Medical College

    Professor,

    Department of Pharmacology

  • Vinod Kumar Verma, Lumbini Medical College

    Associate Professor,

    Department of Pharmacology

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Published

2018-06-27

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Original Research Article

How to Cite

1.
Pattern, Management, and Outcome of Poisoning in a Tertiary Care Hospital. J Lumbini Med Coll [Internet]. 2018 Jun. 27 [cited 2026 Apr. 24];6(1):32-5. Available from: https://jlmc.edu.np/index.php/JLMC/article/view/201

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