Metabolic Syndrome and Benign Prostatic Hyperplasia: A Nepalese Perspective

  • Raj Kumar Chhetri Lumbini Medical College Teaching Hospital, Kathmandu University https://orcid.org/0000-0002-3123-2053
  • Suman Baral Lumbini Medical College Teaching Hospital
  • Neeraj Thapa Lumbini Medical College Teaching Hospital
Keywords: benign prostatic hyperplasia, lower urinary tract symptoms, metabolic syndrome, triglycerides

Abstract

Introduction: Metabolic syndrome is defined as the presence of at least 3 of the following parameters: (1) waist circumference ≥ 90 cm, (2) triglycerides > 150 mg/dl or treatment for hypertriglyceridemia, (3) HDL-cholesterol < 40 mg/dl or treatment for reduced HDL-cholesterol, (4) blood pressure ≥ 130/85 mmHg or current use of antihypertensive medications, (5) fasting blood glucose ≥ 110 mg/dl or previous diagnosis of type-2 diabetes mellitus. It is closely associated with many diseases and recent studies have also shown its association with benign prostatic hyperplasia and lower urinary tract symptoms. Our study aimed to investigate association between metabolic syndrome and its components with benign prostatic hyperplasia among patients managed surgically in a tertiary centre in Western Nepal.

Methods: One hundred and four patients above 50 years with benign prostatic hyperplasia managed in the department of Surgery over one year were included in the study.

Results: Twenty-seven patients had metabolic syndrome (25.96%). There was association between metabolic syndrome and mean prostate size and among components of metabolic syndrome, high serum triglyceride and low HDL Cholesterol were found to be associated. There was increase in mean prostate size with increase in number of metabolic syndrome components which was statistically significant.

Conclusion: Metabolic syndrome along with its two components, serum triglyceride and HDL Cholesterol were associated with increase in mean prostate size.

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Author Biographies

Raj Kumar Chhetri, Lumbini Medical College Teaching Hospital, Kathmandu University

Associate Professor and Head,

Department of Surgery

Suman Baral, Lumbini Medical College Teaching Hospital

Lecturer,

Department of Surgery

Neeraj Thapa, Lumbini Medical College Teaching Hospital

Assistant Professor,

Department of Surgery

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Published
2018-07-18
How to Cite
1.
Chhetri R, Baral S, Thapa N. Metabolic Syndrome and Benign Prostatic Hyperplasia: A Nepalese Perspective. J Lumbini Med Coll [Internet]. 18Jul.2018 [cited 14Jan.2025];6(2):58-1. Available from: https://jlmc.edu.np/index.php/JLMC/article/view/207
Section
Original Research Article