Impact of Lockdown of COVID 19 Pandemic in Pregnancy Outcomes in a Tertiary Care Centre: What to expect?

  • Anjali Subedi Manipal College of Medical Sciences, Pokhara, Nepal.
  • Poonam Magar Manipal College of Medical Sciences, Pokhara, Nepal.
  • Junu Shrestha Manipal College of Medical Sciences, Pokhara, Nepal.
  • Seema Subedi Johns Hopkins Bloomberg School of Public Health, USA.
Keywords: COVID 19, Lockdown, Pandemic, Pregnancy outcome


Introduction: Corona Virus Disease 19 (COVID-19) was declared a "pandemic" in March 2020 by WHO and advocated lockdown measures with the use of mask, frequent hand washing and social distancing for decreasing the transmission of disease. In Nepal where antenatal coverage is just 50% and institutional deliveries 54%, this lockdown has further reduced the regular antenatal visits, institutional deliveries posing an increased adverse effect in pregnancy outcome. This study aimed to reveal the impact of lockdown in pregnancy outcomes in a tertiary care center. Methods: It was a cross-sectional, analytical study done in the Department of Obstetrics and Gynecology, Manipal Teaching Hospital for three months lockdown period (March 2020 to June 2020) and total deliveries along with maternal and perinatal complications were studied in the lockdown period and compared with those in non-lockdown period. Results: During the lockdown period, there were total 1070 deliveries and maternal complication was seen in 17.38% of deliveries. In the non-lockdown period, there were total of 982 deliveries and maternal complication was present in 18.43% of deliveries (p= 0.53). In the study, more cases of early pregnancy complications were seen in lockdown period than in non-lockdown period. Regarding obstetric complications, hypertensive disorder was the most common one observed during lockdown period whereas preterm labor was common in non-lockdown period. There was no increase in perinatal complications during lockdown period on comparing to non-lockdown period. Conclusion: There was no increase in adverse pregnancy outcomes during lockdown of COVID 19 pandemic in a tertiary care center. 


Download data is not yet available.

Author Biographies

Anjali Subedi, Manipal College of Medical Sciences, Pokhara, Nepal.

Assistant Professor,

Department of Obstetrics and Gynecology.

Poonam Magar, Manipal College of Medical Sciences, Pokhara, Nepal.

Medical Officer,

Department of Obstetrics and Gynecology.

Junu Shrestha, Manipal College of Medical Sciences, Pokhara, Nepal.

Associate Professor,

Department of Obstetrics and Gynecology.

Seema Subedi, Johns Hopkins Bloomberg School of Public Health, USA.

Faculty Associate,

Global Disease Epidemiology and Control Division, International Health Department.


Dhama K, Khan S, Tiwari R, Dadar M, Malik YS, Singh KP, et al.COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics. Hum Vaccin Immunother. 2020;16(6):1232-38. PMID: 32186952 DOI:

Zhao S, Lin Q, Ran J, Musa SS, Yang G, Wang W, et al. Preliminary estimation of the basic reproduction number of novel coronavirus (2019-ncov ) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak. International Journal of Infectious Diseases. 2020;92(0):214-17. DOI:

World Health Organization. WHO Recommendations on Antenatal Care for a Positive Pregnancy Experience: Summary [Internet]. Geneva, Switzerland: WHO, 2018. [Accessed on 26th September, 2020]. Available from:

Ministry of Health and Population. Department of Health Services, Kathmandu, Nepal. Annual Report 2074/75 (2017/18) [Internet]. Kathmandu, Nepal: Department of Health Services, 2018. [Accessed on 3rd July,2020] Available from:

Martines RB, Ritter JM, Matkovic E, Gary J, Bollweg BC, Bullock H, et al. Pathology and pathogenesis of SARS-Cov-2 associated with fatal coronavirus disease, United States. Emerg Infect Dis. 2020;26(9):2005-15. PMID: 32437316 DOI:

Graham WJ, Afolabi B, Benova L, Campbell OMR, Filippi V, Nakimuli A, et al. Protecting hard-won gains for mothers and and newborns in low- income and middle-income countries in the face of covid-19: call for a service safety net. BMJ Glob Health. 2020;5(6):e002754. PMID: 32499220 DOI:

Muhaidat N, Fram K, Thekrallah F, Qatawneh A, Al-Btoush A. Pregnancy during covid-19 outbreak: The impact of lockdown in a middle-income country on antenatal healthcare and wellbeing. Int J Womens Health. 2020;12(0):1065-73. PMID: 33235516 DOI:

KC A, Gurung R, Kinney MV, Sunny AK, Moinuddin M, Basnet O, et al. Effect of the covid-19 pandemic response on intrapartum care, stillbirth, and neonatal mortality outcomes in Nepal: a prospective observational study. The Lancet Global Health. 2020;8(10):E1273-81. DOI:

Yerger P, Jalloh M, Coltart CEM, King C. Barriers to maternal health services during the Ebola outbreak in three West African countries: a literature review. BMJ Global Health. 2020;5(9):4-10. DOI:

Poudel A. A 200 percent increase in maternal mortality since the lockdown began [Internet]. Kathmandu, Nepal: The Kathmandu Post,2020.[Accessed on March 21,2021]Available from:

Singh AK, Jain PK, Singh NP, Kumar S, Bajpai PK, Singh S, et al. Impact of COVID-19 pandemic on maternal and child health services in Uttar Pradesh, India. J Family Med Prim Care. 2021;10(1):509-13. PMID: 34017779 DOI:

Shapiro GD, Fraser WD, Frasch MG, Séguin JR. Psychosocial stress in pregnancy and preterm birth: associations and mechanisms. J Perinat Med. 2013;41(6):631-45. PMID: 24216160 DOI:

Eick SM, Goin DE, Izano MA, Cushing L, DeMicco E, Padula AM, et al. Relationships between psychosocial stressors among pregnant women in San Fransico: A path analysis. Plos One 2020;15(6):e0234579. PMID: 32530956 DOI:

How to Cite
Subedi A, Magar P, Shrestha J, Subedi S. Impact of Lockdown of COVID 19 Pandemic in Pregnancy Outcomes in a Tertiary Care Centre: What to expect?. J Lumbini Med Coll [Internet]. 3Jan.2022 [cited 22May2022];9(2):6 pages. Available from:
Original Research Article