Kluver-Bucy Syndrome in a Patient with Bipolar Affective Disorder

A Case Report

Authors

  • Madhur Basnet BP. Koirala Institute of Health Sciences, Dharan, Nepal https://orcid.org/0000-0001-9624-0321 (unauthenticated)
  • Luna Paudel Kathmandu Medical College, Sinamangal, Kathmandu
  • Bikram Prasad Gajurel Tribhuwan University Teaching Hospital, Maharajgunj, Kathmandu
  • Nidesh Sapkota B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Raj Kumar Rauniyar B. P. Koirala Institute of Health Sciences, Dharan, Nepal

DOI:

https://doi.org/10.22502/jlmc.v6i1.183

Keywords:

bipolar affective disorder, BPAD, Kluver-Bucy syndrome, mania

Abstract

Introduction: Kluver and Bucy described a behavioral syndrome in rhesus monkeys following bilateral temporal lobectomy which included psychic blindness, hyperorality, hypermetamorphosis, hypersexuality, and emotional unresponsiveness.

Case report: A 44 years old right handed male of Indo-aryan origin, blacksmith by profession, had presented in manic phase of bipolar illness. He had hypersexuality, hypermetamorphosis, hyperorality, and altered dietary habits along with amnesia and fleeting misrecognition of even his close relatives. MRI of the patient showed mild cerebral atrophy with right temporal lobe atrophy. The patient was treated with lithium and olanzapine along with benzodiazepines. The symptoms resolved gradually with resolution of the manic phase. Patient had similar features in the previous manic episode as well that resolved with resolution of mania.

Conclusion: The symptoms of Kluver-Bucy syndrome like increased libido, increased activity might be confused with that of mania. Other features of Kluver-Bucy syndrome and the overt hypersexuality could help identify it even during manic phase of bipolar illness.

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Author Biographies

  • Madhur Basnet, BP. Koirala Institute of Health Sciences, Dharan, Nepal

    Assistant Professor,

    Department of Psychiatry

  • Luna Paudel, Kathmandu Medical College, Sinamangal, Kathmandu

    Department of Psychiatry

  • Bikram Prasad Gajurel, Tribhuwan University Teaching Hospital, Maharajgunj, Kathmandu

    Department of Neurology

  • Nidesh Sapkota, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

    Department of Psychiatry

  • Raj Kumar Rauniyar, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

    Professor,

    Department of Radiodiagnosis and Imaging

photo image of Madhur Basnet

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Published

2018-03-30

Issue

Section

Case Report

How to Cite

1.
Kluver-Bucy Syndrome in a Patient with Bipolar Affective Disorder: A Case Report. J Lumbini Med Coll [Internet]. 2018 Mar. 30 [cited 2026 Apr. 16];6(1):36-40. Available from: https://jlmc.edu.np/index.php/JLMC/article/view/183