Nairobi Eye: A Clinico-epidemiological Study from A Tertiary Care Center of Central Nepal
Abstract
Introduction: Periocular paederus dermatitis (Nairobi eye) is characterized by erythematous vesiculobullous
linear plaque with stinging sensation. It commonly occurs during rainy season. It has been described
in people living near agricultural fields due to the potential toxin pederin. This study aims to evaluate the
demographic profile and clinical presentation of patients with periocular paederus dermatitis in a tertiary care
center. Methods: This was a descriptive, cross-sectional study evaluating patients attending dermatology
and/or ophthalmology department with features consistent with paederus dermatitis involving periocular
area from June to August, 2019. Relevant demographic and clinical data were obtained; clinical photographs
were taken and histopathology performed among selected patients. Results: A total of 24 (14.8%) patients had
features of Nairobi eye among 162 patients of paederus dermatitis. Majority of the patients were males (1.4:1)
with mean age 29.08±13.38 years. The peak time of presentation was the first week of July (37.5%). Mean
time period between onset of symptoms and presentation was 3.41±2.01 days. The lesions were unilateral in
all cases, with predominant involvement of the right eye (62%). Burning sensation (80%) and itching (60%)
were the predominant symptoms while conjunctival hyperemia (41.6%), seropurulent discharge (20.8%)
and chemosis (16.6%) were the ocular findings. Most of the patients (n=17, 70.8%) noticed the lesion while
waking up in the morning. Conclusion: The finding of the present study has shown that Nairobi eye is
a common presentation during rainy season. Periocular findings with significant intraocular signs were
documented to be presenting features among patients with periocular paederus dermatitis.
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References
Karthikeyan K, Kumar A. Paederus dermatitis. Indian J Dermatol Venereol Leprol. 2017;83(4):424-431. DOI: https://doi.org/10.4103/0378-6323.198441. PMID: 28584222.
Narasimhalu CR, Murali A, Kannan R, Srinivasan N. Blister beetle dermatitis. J Indian Med Assoc. 2010;108(11):781-2. PMID: 21510580.
Fakoorziba MR, Eghbal F, Azizi K, Moemenbellah-Fard MD. Treatment outcome of Paederus dermatitis due to rove beetles (Coleoptera: Staphylinidae) on guinea pigs. Trop Biomed. 2011;28(2):418-24. PMID: 22041764.
Mbonile L. Acute haemorrhagic conjunctivitis epidemics and outbreaks of Paederus spp. keratoconjunctivitis (‘Nairobi red eyes’) and dermatitis. S Afr Med J. 2011;101(8):541-3. PMID: 21920128.
Beaulieu BA, Irish SR. Literature review of the causes, treatment, and prevention of dermatitis linearis. J Travel Med. 2016;23(4):taw032. DOI: https://doi.org/10.1093/jtm/taw032.
Schunkert EM, Aschoff NS, Grimmer F, Wiemann C, Zillikens D. Paederus dermatitis - touched by champion flies - three clinical manifestations of pederin toxin-inflicted dermatitis. Int J Dermatol. 2018;57(8):989-991. DOI: https://doi.org/10.1111/ijd.13968. PMID: 29603192.
Maryam S, Fadzly N, Zuharah WF. The Effects of Light and Height of Building in Attracting Paederusfuscipes Curtis to Disperse towards Human Residential Areas. Trop Life Sci Res. 2016;27(supp1):95-101. DOI: https://doi.org/10.21315/tlsr2016.27.3.13. PMID: 27965746.
Prasher P, Kaur M, Singh S, Kaur H, Bala M, Sachdeva S. Ophthalmic manifestations of Paederus dermatitis. Int Ophthalmol. 2017;37(4):885‐891. DOI: https://doi.org/10.1007/s10792-016-0352-y. PMID: 27628585.
Srihari S, Kombettu AP, Rudrappa KG, Betkerur J. Paederus Dermatitis: A Case Series. Indian Dermatol Online J. 2017;8(5):361-364. DOI: https://doi.org/10.4103/idoj.IDOJ_238_16. PMID: 28979873.
Bong LJ, Neoh KB, Jaal Z, Lee CY. Life table of Paederus fuscipes (Coleoptera: Staphylinidae). J Med Entomol. 2012;49(3):451-60. DOI: https://doi.org/10.1603/me11163. PMID: 22679850.
Uzunoğlu E, Oguz ID, Kir B, Akdemir C. Clinical and Epidemiological Features of Paederus Dermatitis Among Nut Farm Workers in Turkey. Am J Trop Med Hyg. 2017;96(2):483- 487. DOI: https://doi.org/10.4269/ajtmh.16-0582. PMID: 27879459. PMCID: PMC5303057.
Assaf M, Nofal E, Nofal A, Assar O, Azmy A. Paederus dermatitis in Egypt: a clinicopathological and ultrastructural study. J Eur Acad Dermatol Venereol. 2010;24(10):1197- 201. DOI: https://doi.org/10.1111/j.1468- 3083.2010.03621.x. PMID: 20236196.
Cressey BD, Paniz-Mondolfi AE, Rodríguez- Morales AJ, Ayala JM, De Ascenção Da Silva AA. Dermatitis linearis: vesicatingdermatosis caused by paederus species (coleoptera: staphylinidae). Case series and review. Wilderness Environ Med. 2013;24(2):124-31. DOI: https://doi.org/10.1016/j.wem.2012.11.005. PMID: 23352312.
Panta YR, Poudyal Y. A case report of a self-reproduced case of Paederus dermatitis. Journal of Universal College of Medical Sciences. 2013;1(4):48-52. DOI: https://doi.org/10.3126/jucms.v1i4.9575.
Canan H, Altan-Yaycioglu R, Durdu M. PeriocularPaederus dermatitis mimicking preseptal cellulitis. Can J Ophthalmol. 2013;48(2):121-5. DOI: https://doi.org/10.1016/j.jcjo.2012.10.004. PMID: 23561606.
Verma S, Gupta S. Ocular manifestations due to econda (Paederussabaeus). Med J Armed Forces India. 2012;68(3):245-8. DOI: https://doi.org/10.1016/j.mjafi.2011.11.006. PMID: 24532878.

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