COVID-19: Intranasal and Oral Routes of Vaccination

Keywords: Biological Products, COVID 19 Vaccines, Immunization, SARS-Co-V 2

Abstract

The mainstay protocol exercised by global health leaders to control the spread of severe acute respiratory syndrome corona virus (SARS-CoV-2) has been screening, the identification of cases, isolation thereof, contact tracing and nation-wide lockdowns. The development of vaccinations against the SARS-CoV-2 virus has marked a new dawn for the war against corona virus disease (COVID-19).

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Author Biographies

Jared Robinson, Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, Mauritius

Medical student.

Alexandra Leclézio, Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, Mauritius

Medical student.

Indrajit Banerjee, Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, Mauritius

Associate Professor,

Department of Pharmacology.

References

Banerjee I, Robinson J, Kashyap A, Mohabeer P, Shukla A, Leclézio A. The changing pattern of COVID-19 in Nepal: A Global concern-A Narrative Review. Nepal J Epidemiol. 2020;10(2):845-55. PMCID: PMC7423402 PMID: 32874698 DOI: https://doi.org/10.3126/nje.v10i2.29769

Fauci AS, Lane HC, Redfield RR. Covid-19 - Navigating the Uncharted. N Engl J Med. 2020;382(13):1268-9. PMID: 32109011 DOI: https://doi.org/10.1056/NEJMe2002387

Peiris M, Leung GM. What can we expect from first-generation COVID-19 vaccines? Lancet. 2020;396(10261):1467-9. PMID: 32971042 DOI: https://doi.org/10.1016/S0140-6736(20)31976-0

Ku MW, Bourgine M, Authié P, Lopez J, Nemirov K, Moncoq F, et al. Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models. Cell Host Microbe. 2021;29(2):236-249.e6. PMID: 33357418 DOI: https://doi.org/10.1016/j.chom.2020.12.010

Wang J, Peng Y, Xu H, Cui Z, Williams RO 3rd. The COVID-19 Vaccine Race: Challenges and Opportunities in Vaccine Formulation. AAPS Pharm Sci Tech. 2020;21(6):225. PMID: 32761294 DOI: https://doi.org/10.1208/s12249-020-01744-7

Pharmaceutical Technology. Oramed forms joint venture to develop new oral vaccines for Covid-19. Available from: https://www.pharmaceutical-technology.com/news/oramed-joint-venture-oral-vaccines/ (Accessed 7 April 2021).

Bharat Biotech. BBV154. Available from: https://www.bharatbiotech.com/intranasal-vaccine.html (Accessed 7 April 2021).

Financial Times. Trial set to start of AstraZeneca Covid vaccine as nasal spray. Available from: https://www.ft.com/content/48fe2e97-f9e5-4291-b965-0728bfc42213 (Accessed 7 April 2021).

Joi P. COVID-19 vaccines: could a squirt up the nose be just as good as a shot in the arm? Available from: https://www.gavi.org/vaccineswork/covid-19-vaccines-could-squirt-nose-be-just-good-shot-arm (Accessed 7 April 2021).

Collins FM. Factoring patient compliance into oral care. RDH. 2008;28(4):15-26. Available from: https://www.rdhmag.com/magazine/542082

Weir E, Hatch K. Preventing cold chain failure: vaccine storage and handling. CMAJ. 2004;171(9):1050. PMID: 15505266 DOI: https://doi.org/10.1503/cmaj.1041565

Sookaromdee P, Wiwanitkit V. New COVID-19 Vaccines, Its Cost and Shelf Life: A Cost Effectiveness Analysis. Arch Med Res. 2020;S0188-4409(20):32249-9. PMID: 33485639 DOI: https://doi.org/10.1016/j.arcmed.2020.12.008

Published
2021-05-10
How to Cite
1.
Robinson J, Leclézio A, Banerjee I. COVID-19: Intranasal and Oral Routes of Vaccination. J Lumbini Med Coll [Internet]. 10May2021 [cited 28Jul.2021];9(1):3 pages. Available from: https://jlmc.edu.np/index.php/JLMC/article/view/427
Section
Perspective