Echocardiographic profile of patients with cardiomyopathy
Abstract
Introduction: Cardiomyopathies represent a heterogeneous group of diseases that often lead to progressive heart failure with significant morbidity and mortality. Exact epidemiological data on cardiomyopathy in Nepal are lacking. This study was done to observe the demographic and echocardiographic profile of patients with cardiomyopathy attending a medical college teaching hospital.
Methods: Trans-thoracic two-dimensional echocardiographic study was performed by first author on all patients with cardiomyopathy over a period of six months. Patients’ demographic and echocardiographic data were collected and analyzed using SPSS version 20 software. Student t-test and Chi-square test were applied where appropriate.
Results: A total of 60 patients were studied from October 2017 to March 2018. Mean age of all participants was 56.38 years (SD = 13.86). Mean age of males was significantly higher than that of females (60.96 yrs, SD = 13.61 versus 51.62 yrs, SD = 13.47) in dilated cardiomyopathy subgroup (p < 0.05). Of all patients, 32 (53.33%) had dilated cardiomyopathy (idiopathic) and 13 (21.66%) had ischemic cardiomyopathy.
Conclusion: Our study highlighted significant burden of dilated cardiomyopathy. Dilated cardiomyopathy appeared in females at earlier age compared to males. Potentially reversible cardiomyopathies like alcoholic and peripartum cardiomyopathies were also present which have a probability of cure if treated properly.
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References
Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E. A Braunwald's heart disease -Textbook of Cardiovascular Medicine: Dilated cardiomyopathy. 10th Ed.Philadelphia: Elsivier Saunders;2015, pp.1551-62.
Elliott P, Andersson B, Arbustini E, et al: Classification of the cardiomyopathies: A position statement from the European Society of Cardiology Working Group on Myocardial and Pericardial diseases. Eur Heart J 29:270, 2008.
Maron BJ, Towbin JA, Thiene G, et al. Contemporary Definitions and Classification of the Cardiomyopathies. Circulation 2006;113:1807-16.
Go As, Mozaffarian D, Roger VL. Heart disease and stroke statistics-2013 update:A report from the American Heart Association. Circulation 127:e6, 2013
Rubin E. Alcohol and the heart. N Engl J Med. 1979 ; 301 : 28-33
Anderson KM, Kannel WB. Prevalence of congestive heart failure in Framingham Heart study subjects. Circulation 1994;13:S107-S112
Cohn JN, Bristow MR, Chien KR. Report of the national heart, lung, and blood institute special emphasis panel on heart failure research. Circulation 1997;95:766-70.
Kalon K.L., Keaven M. Anderson, William B. Kannel, William Grossman, Daniel Levy. Survival After the Onset of Congestive Heart Failure in Framingham Heart Study Subjects. Circulation 1993;88:107-115.
Feigenbaum H, Armstrong WF, Rayn T. Dilated and Hypertrophic cardiomyopathy. Feigenbaum’s Echocardiography, 7th Asian edition 2010 Philadelphia. Wolters Kluwer. 507–60.
Randy Wexler, Terry Elton, Adam Pleister, David Feldman. Cardiomyopathy: An Overview. Am Fam Physician. 2009; 79(9): 778–84.
Praful JD, Sachin MN.Clinical profile of patients with dilated cardiomyopathy-A study of 50 cases. Journal of Research in Medical and Dental Sciences. 2016; 4(3)
Ahmad S, Rabbani M, Zaheer M, Shirazi N. Clinical ECG and echocardiographic profile of patients with dilated cardiomyopathy. Indian J Cardiol. 2005;8:25-9.
Pacheco OE, Novoa JE, Cox RA. Dilated cardiomyopathy: a clinical review of patients evaluated at a tertiary care center in Puerto Rico. P R Health Sci J. 1995;14(4): 269–73.
Codd MB, Sugrue DD, Gersh BJ and Melton LJ. Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. A population-based study in Olmsted County, Minnesota. 1975–1984. Circulation. 1989; 80: 564–72.
Hasan AH, Qureshi A, Ramejo BB, et al. Peripartum cardiomyopathy characteristics and outcome in a tertiary care hospital. JPMA. 2010: 60; 377–80.
Ntobeko B A Ntusi, Ambroise Wonkam, Gasnat Shaboodien, Motasim Badri, Bongani M Mayosi. Frequency and clinical genetics of familial dilated cardiomyopathy in Cape Town: Implications for the evaluation of patients with unexplained cardiomyopathy. S Afr Med J. 2011;101: 1–5.
Haq Nawaz, Rehan Ahmed, Nasir Ahmed, Abdul Rashid. Frequency Of Echocardiographic Complications Of Dilated Cardiomyopathy At A Tertiary Care Hospital. J Ayub Med Coll Abbottabad. 2011; 23(3): 51–5.
Phadke R S, Vaideeswar P, Mittal B, Deshpande J. Hypertrophic cardiomyopathy: an autopsy analysis of 14 cases. J Postgrad Med. 2001; 47:165.
Regan TJ. Alcohol and the cardiovascular system. JAMA, 1990;264:377-381.
Ely M, Hardy R, Longford NT, Wadsworth MEJ.Gender differences in the relationship betweenalcohol consumption and drink problems are largely accounted for by body water. Alcohol and Alcoholism.1999;34:894-902.
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