Pharmacovigilance: Knowledge, Attitude and Practice among Medical Professionals at a Tertiary Care Hospital in Nepal

  • Kamal Kandel Lumbini Medical College and Teaching Hospital https://orcid.org/0000-0002-0451-2607
  • Naresh Karki Lumbini Medical College and Teaching Hospital
  • Kyushu Shah Lumbini Medical College and Teaching Hospital
  • Pravin Prasad Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Keywords: Adverse drug reactions, Attitude, Knowledge, Medical professionals, Pharmacovigilance, Practice

Abstract

Introduction: Awareness regarding pharmacovigilance and adverse drug reaction reporting by medical professionals significantly contribute to the safer use of medicine. Therefore, the objective of this study was to assess the knowledge, attitude, and practices regarding pharmacovigilance among the medical professionals at a tertiary care hospital in Nepal. Methods: This study was a descriptive cross-sectional study conducted at Lumbini Medical College and Teaching Hospital. Printed questionnaires were distributed to all the medical professionals and collected data were analyzed to find the knowledge, attitude, and practices of the medical professionals regarding pharmacovigilance. Results: A total of 107 medical professionals, 77 (71.96%) males and 30 (28.04%) females, participated in the study. The overall response rate was 98.16%. In this study,70.1% of medical professionals knew the definition of pharmacovigilance, and more than half of the participants(63.6%) did not know the existence of the national pharmacovigilance center. Regarding attitude, 52.3% of the medical professionals strongly agreed that adverse drug reaction reporting and monitoring systems were beneficial to patients or improved patient care. Half of the medical professionals would sometimes counsel the patients about adverse drug reactions. Almost half of  medical professionals mentioned that the major factor behind underreporting was insufficient knowledge of where to report adverse drug reactions. Training on pharmacovigilance was the main recommendation from the participants (52.3%) to improve the pharmacovigilance program. Conclusion: There is room for improvement in the knowledge, attitude and practice of the participants. Most medical professionals suggested training or continuing medical education as a way to improve pharmacovigilance programs.

Downloads

Download data is not yet available.

Author Biographies

Kamal Kandel, Lumbini Medical College and Teaching Hospital

Lecturer,

Department of Pharmacology.

Naresh Karki, Lumbini Medical College and Teaching Hospital

Assistant Professor,

Department of Pharmacology.

Kyushu Shah, Lumbini Medical College and Teaching Hospital

Lecturer,

Department of Pharmacology.

Pravin Prasad, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.

Assistant Professor,

Department of Pharmacology.

References

Bhagavathula AS, Elnour AA, Jamshed SQ, Shehab A. Health Professionals’ Knowledge, Attitudes and Practices about Pharmacovigilance in India: A Systematic Review and Meta-Analysis. PloS One. 2016;11(3):e0152221.PMID: 27010447 DOI: https://doi.org/10.1371/journal.pone.0152221

Srinivasan V, SheelaD, Mridula D. Knowledge, attitude and practice of pharmacovigilance among the healthcare professionals in a tertiary care hospital- A questionnaire study. Biomedical and Pharmacology Journal. 2017;10(3):1441-47. DOI: https://dx.doi.org/10.13005/bpj/1251

Paveliu MS, Bengea-Luculescu S, TomaM,Paveliu SF. Perception on adverse drug reaction reporting by physicians working in southern Romania. Maedica (Bucur). 2013;8(1):17-25.PMID: 24023593 PMCID: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3749755/

Katekhaye VM, Kadhe NG, John J,Pawar SR. Knowledge, attitude and practice of pharmacovigilance among medical professionals at a tertiary care hospital in Mumbai, Maharashtra, India. International Journal of Research in Medical Sciences. 2017;5(1):156-61. DOI:https://dx.doi.org/10.18203/2320-6012.ijrms20164540

KC S, Tragulpiankit P, Gorsanan, Edwards IR. Attitudes among healthcare professionals to the reporting of adverse drug reactions in Nepal. BMC Pharmacol Toxicol. 2013;14(0):16. PMID: 23497690 DOI: https://doi.org/10.1186/2050-6511-14-16

Bista N. Pharmacovigilance in Nepal [Internet]. Nepal: Pharma Info Nepal, 2020.[Accessed on 23rd September, 2021]Available from: https://pharmainfonepal.com/pharmacovigilance-in-nepal/

KC S, Tragulpiankit, Edwards IRP, Gorsanan S. Knowledge about adverse drug reactions reporting among healthcare professionals in Nepal. Int J Risk Saf Med. 2013;25(1):1-16. PMID: 23442293 DOI: https://doi.org/10.3233/jrs-120578

Bhavana A, Sekhar DG, Rekha M, Gopinath C. Reasons for underreporting adverse drug reactions: A review. Journal of Pharmacovigilance.2014;2(5):128. Available from: https://www.longdom.org/conference-abstracts-files/2329-6887.S1.014-021.pdf

Palaian S, Ibrahim MI, Mishra P. Health professionalsˈ knowledge, attitude and practices towards pharmacovigilance in Nepal. Pharmacy Pract (Granada). 2011;9(4):228-35. PMID: 24198861 DOI: https://doi.org/10.4321/s1886-36552011000400008

Kunnoor NS, Singanal S,Lohit K. Perception of doctors towards Adverse Drug Reaction (ADR) reporting: A cross sectional survey using a validated questionnaire. International Journal of Basic&Clinical Pharmacology. 2017;6(11):2671-5. DOI:https://dx.doi.org/10.18203/2319-2003.ijbcp20174786

Shroukh WA, Shakhatreh FM, YaseinNA,Sharkas GF. A survey on the knowledge, attitudes and practices of physicians towards pharmacovigilance in Jordanian health centres. Int Health. 2018;10(5):363-70. PMID: 29718320 DOI: https://doi.org/10.1093/inthealth/ihy029

Alshammari TM, Almoslem MJ. Knowledge, attitudes & practices of healthcare professionals in hospital towards the reporting of adverse drug reaction in Saudi Arabia: A multi centre cross sectional study. Saudi Pharma J. 2018;26(7):925-31. PMID: 30416347 DOI: https://doi.org/10.1016/j.jsps.2018.04.012

Alsaleh FM, Alzaid SW, Abahussain EA, Bayoud T, Lemay J. Knowledge, attitude and practices of pharmacovigilance and adverse drug reaction reporting among pharmacists working in secondary and tertiary governmental hospitals in Kuwait. Saudi pharm J. 2017;25(6):830-37.PMID: 28951666 DOI: https://doi.org/10.1016/j.jsps.2016.12.004

Gupta P,Udupa A. Adverse drug reaction reporting and pharmacovigilance: Knowledge, attitudes and perceptions amongst resident doctors. Journal of Pharmaceutical Science and Research. 2011;3(2):1064-69. Available from: https://www.jpsr.pharmainfo.in/Documents/Volumes/Vol3Issue02/jpsr%2003110205.pdf

Gupta SK, Nayak RP, Shivaranjani R,Vidyarthi SK. A questionnaire study on the knowledge, attitude and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India. Perspect Clin Res. 2015;6(1):45-52. PMID: 25657902 DOI: https://doi.org/10.4103/2229-3485.148816

Oshikoya KA, Awobusuyi JO. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol. 2009;9(0):14.PMID: 19671176 DOI: https://doi.org/10.1186/1472-6904-9-14

Ekman E, Bȁckstrőm M. Attitudes among hospital physicians to the reporting of adverse drug reactions in Sweden. Eur J ClinPharmacol. 2009;65(1):43-6.PMID: 18825377 DOI: https://doi.org/10.1007/s00228-008-0564-9

Das L, Bhattacharjee P, Ghosh R, Das UK, Ray T. Knowledge, attitude and practice of pharmacovigilance among doctors in a tertiary care teaching hospital of Tripura. Nationall Journal of Physiology, Pharmacy and Pharmacology. 2017;7(2):218-23. https://www.researchgate.net/publication/311997199

Mishra PS,Gudsurkar G. Cross sectional study to assess the awareness of pharmacovigilance among post graduate residents of tertiary care medical college hospital of central India.International Journal of Basic&Clinical Pharmacology. 2018;7(3):386-90. DOI:https://dx.doi.org/10.18203/2319-2003.ijbcp20180501

Published
2021-12-30
How to Cite
1.
Kandel K, Karki N, Shah K, Prasad P. Pharmacovigilance: Knowledge, Attitude and Practice among Medical Professionals at a Tertiary Care Hospital in Nepal. J Lumbini Med Coll [Internet]. 30Dec.2021 [cited 17Jan.2022];9(2):6 pages. Available from: https://jlmc.edu.np/index.php/JLMC/article/view/452
Section
Original Research Article